Fig. 12

DNET in a 24-week foetus with elective termination of pregnancy. (a) Sagittal T1W MRI, (b) axial T2W MRI showing ventriculomegaly (asterisks) and a dysplastic mesencephalon (arrows), which were the cause of TOP. c Macroscopic specimen. d Tumour with DNET features involving the brainstem with infiltration of the Silvius aqueduct (H/E, ×4). e, f Double staining showing positivity for neurofibrils (immunohistochemistry against neurofibrils, in brown) intermingled with mucoid material (alcian blue, in blue) in the tumour (×40 and ×20)