Table 2 Examples of studies with a direct contribution to patient carea,b
| References | Primary research area | Description study | Category | Workload |
|---|---|---|---|---|
| [16] | Neuroradiology |
Study purpose: “To assess diagnostic accuracy of MR neurography in the differential diagnosis of amyotrophic lateral sclerosis (ALS) and multifocal motor neuropathy (MMN)” Study conclusion: “MR neurography is an accurate method for assisting in the differential diagnosis of ALS and MMN” | Completely new imaging application | Increases (new imaging application) |
| [17] | Chest |
Study purpose: “This study analyzed phantom and human chronic obstructive pulmonary disease (COPD) data to test the hypothesis that ultra-high-resolution computed tomography (U-HRCT) can accurately measure peripheral airways that are difficult to measure with conventional CT” Study conclusion: “U-HRCT enables accurate and direct evaluation of peripheral airways 1–2 mm in diameter. The 6th generation airways are commonly < 2 mm in diameter, and the sum-LA can be a useful CT biomarker that reflects airflow limitation in COPD” | Another type of imaging as an alternative for an existing imaging application | Increases (longer interpretation time than conventional HRCT) |
| [18] | Nuclear medicine |
Study purpose: “The aim of this study was to investigate the diagnostic performance of whole-body [C]acetate PET/CT in less aggressive or indolent lymphomas, wherein [F]FDG PET/CT would exhibit limited sensitivity” Study conclusion: “[C]acetate PET/CT exhibited greater sensitivity than [F]FDG PET/CT for lesion detection in patients with less aggressive or indolent lymphomas, thus promising applicability as a physiological tracer in the study of such lesions” | Another type of imaging as an alternative for an existing imaging application | No change |
| [19] | AI |
Study purpose: “Focal pattern in multiple myeloma (MM) seems to be related to poorer survival and differentiation from diffuse to focal pattern on CT has inter-reader variability. We postulated that a radiomic approach could help radiologists in differentiating diffuse from focal patterns on CT” Study conclusion: “A radiomics approach improves radiological evaluation of focal and diffuse pattern of MM on CT” | Elaboration of an existing imaging application | Increases (longer post-processing and interpretation time) |
| [20] | Musculoskeletal |
Study purpose: “To assess how many and which CT reformats of long bone non-unions should be analyzed to best approximate the analysis of a larger number of CT reformats obtained in the three orthogonal planes” Study conclusion: “Semi-quantitative analysis of the two paramedian sagittal and coronal CT reformats is an acceptable alternative to the analysis of more numerous reformats” | Elaboration of an existing imaging application | Decreases (shorter interpretation time) |
| [21] | Cardiac |
Study purpose: “To investigate the clinical utility of our newly developed contrast enhancement optimizer (CEO) software for coronary CT angiography (CCTA)” Study conclusion: “The use of our CEO for CCTA studies yielded optimal aortic contrast enhancement in significantly more patients than the standard protocol based on the body weight” | Elaboration of an existing imaging application | No change |