Skip to main content

Table 2 Primary clinical or mpMRI characteristics of prostatic abnormalities

From: Differential diagnosis of uncommon prostate diseases: combining mpMRI and clinical information

Prostatic abnormalities Primary clinical or mpMRI characteristics
Acinar adenocarcinoma with/without other glandular neoplasms Age: elderly men
PSA: sharply elevated
PI-RADS: suitable
BPH Age: elderly men
PSA: slightly elevated
PI-RADS: suitable
Chronic prostatitis PSA: slightly elevated
PI-RADS: suitable
Benign hyperplastic nodules outside the TZ PSA: Slightly elevated
PI-RADS: unsuitable
Granulomatous prostatitis Past relevant history: iatrogenic causes (after surgical operations or BCG therapy for urothelial carcinoma) and allergy
PSA: transiently elevated
PI-RADS: unavoidable
Prostate tuberculosis Past relevant history: BCG therapy for urothelial carcinoma
Symptoms: active tuberculosis in other organs or systems
PSA: transiently elevated
PI-RADS: unsuitable
Abscess Symptoms: fever, chills, urinary frequency and urgency, suprapubic pain, and pus cells on urine examination
PSA: transiently elevated
mpMRI findings: central necrosis in the interior presenting with hyperintensity on T2WI, hyperintensity on high b-value DWI, and low ADC, with rim enhancement in the exterior
PI-RADS: unsuitable
Mesenchymal tumors Age: younger men
PSA: normal
mpMRI findings: hemorrhagic, cystic or necrotic changes with complete or incomplete capsule causing distinct mass effects
PI-RADS: unsuitable
Lymphoma PSA: normal
Symptoms: LUTS, systemic symptoms (including fever, chills, night sweats, and weight loss)
PI-RADS: unavoidable
Prostatic cystadenoma Age: large age range
mpMRI findings: cystic lesions
PI-RADS: unsuitable
  1. PSA prostate-specific antigen, PI-RADS Prostate Imaging Reporting and Data System, BPH benign prostatic hyperplasia, TZ transitional zone, BCG bacillus Calmette–Guérin, mpMRI multiparametric magnetic resonance imaging, T2WI T2-weighted imaging, DWI diffusion-weighted imaging, ADC apparent diffusion coefficient, LUTS lower urinary tract symptoms