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Table 4 Risk of lymph node and distant metastasis with MRI-detected extramural venous invasion

From: MRI-detected extramural venous invasion of rectal cancer: Multimodality performance and implications at baseline imaging and after neoadjuvant therapy

Authors Year No. of patients Treatment MRI timing Endopoint Summary of results
Koh [23] 2008 79 No Pre surgery Nodal disease Sv: 0.56 (0.79–0.96) Sp: 0.81 (0.69–0.90)
Liu [27] 2016 183 No Pre surgery Nodal disease OR: 4.22 (1.79–9.95)
Bugg [66] 2014 202 No data Pre surgery Metachronous metastasis RR: 3.70 (95%CI: NA)
Sohn [24] 2015 447 nCRT (9.2%: 41/447) Pre nCRT Synchronous metastasis OR:3.02 (1.65–5.51)
  1. nCRT, neoadjuvant chemoradiation therapy; R, odds ratio; RR, relative risk; Sp, specificity; Sv, sensitivity