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Table 2 Estimated Performance of MRI for extramural venous invasion

From: MRI-detected extramural venous invasion of rectal cancer: Multimodality performance and implications at baseline imaging and after neoadjuvant therapy

Authors Year No. of patients No. of readers Pulse sequences Sensitivity Specificity Inter-observer agreement
Before neoadjuvant therapy
Smith [22] 2008 142 1 T2WI 0.62 0.88 NA
Koh [23] 2008 79 NA T2WI 1.00 0.89 NA
Sohn [24] 2015 447 NA T2WI 0.282 0.94 NA
Jhaveri [26] 2016 49 2 T2WI, CE-T1WI T2WI alone: 0.43–0.50
T2WI + CE-T1WI: 0.57
T2WI alone: 0.96–1.00
T2WI + CE-T1WI: 0.96
T2WI alone: 0.828
T2WI + CE-T1WI: 0.858
Liu [27] 2016 183 2 T2WI 0.617 0.820 0.780
Yu [28] 2016 86 2 T2WI 0.583 0.920 0.803
Lee [29] 2018 200 2 T2WI 0.9048 0.4114 0.801
Liu [30] 2016 59 2 T2WI, CE-T1WI T2WI alone: 0.500–0.722
CE-T1WI alone: 0.556 T2WI + CE-T1WI:0.778–0.833
T2WI alone: 0.732–0.780
CE-T1WI alone: 0.659–0.683 T2WI + CE-T1WI: 0.732–0.756
T2WI alone: 0.603
CE-T1WI alone: 0.216 T2WI + CE-T1WI: 0.413
Ahn [32] 2019 79 2 T2WI, DWI T2WI alone: 0.80–0.85 T2WI alone: 0.53–0.75 T2WI alone: 0.704
      T2WI + DWI: 0.90 T2WI + DWI: 0.54–0.66 T2WI + DWI: 0.611
Bae [31] 2019 147 3 T2WI, CE-T1WI T2WI + CE-T1WI: 0.720–0.840 T2WI + CE-T1WI:  0.454–0.856 T2WI + CE-T1WI: 0.376–0.693
Fornell-Perez [45] 2020 54 3 T2WI, DWI T2WI alone: 0.571
T2WI + DWI: 0.476
T2WI alone: 0.759
T2WI + DWI: 0.872
T2WI alone: 0.483
T2WI + DWI: 0.438
After neoadjuvant therapy
Jhaveri [26] 2016 20 2 T2WI, CE-T1WI T2WI alone: 0.29 T2WI alone: 0.95–1.00 T2WI alone: 0.781
      T2WI + CE-T1WI: 0.43–0.57 T2WI + CE-T1WI: 0.95 T2WI + CE-T1WI: 0.604
Lee [29] 2018 200 2 T2WI 0.7619 0.7975 0.736
Fornell-Perez [45] 2020 46 3 T2WI, DWI T2WI alone: 0.667
T2WI + DWI: 0.778
T2WI alone: 0.829
T2WI + DWI: 0.915
T2WI alone: 0.372
T2WI + DWI: 0.361
Bae [31] 2019 75 3 T2WI, CE-T1WI T2WI + CE-T1WI: 0.667–0.792 T2WI + CE-T1WI: 0.490–0.922 T2WI + CE-T1WI: 0.383–0.693
  1. CE-T1WI, contrast enhanced T1-weighted image; DWI, diffusion-weighted image; T2WI, T2-weighted image