Skip to main content

Table 1 Timeline, symptoms, and imaging findings of radiation-induced brain injury [11,12,13,14]

From: Imaging side effects and complications of chemotherapy and radiation therapy: a pictorial review from head to toe

  Acute Early Delayed Late delayed
Onset Days/weeks after RT
Reversible
1–4 months after RT
Reversible
6 months after RT
Not reversible
Symptoms Headache
Nausea and vomiting
Transient neurological deficits
Somnolence
Transient cognitive deficits and memory loss
Focal or diffuse neurological defects
Progressive cognitive impairment
Imaging findings Inapparent Inapparent
Pseudoprogression
Leukoencephalopathy
Parenchymal atrophy
Radionecrosis
Vascular disorders (stroke, Moyamoya, mineralizing microangiopathy, capillary telangiectasias, cavernous malformations)
Secondary tumors
Transient focal enhancing lesions
Stroke-like migraine attacks after radiation therapy (SMART)