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Fig. 27 | Insights into Imaging

Fig. 27

From: Imaging side effects and complications of chemotherapy and radiation therapy: a pictorial review from head to toe

Fig. 27

A 68-year-old man with Hodgkin Lymphoma treated with ChT (including high doses of corticosteroids) and atraumatic right hip pain. Coronal T1-weighted (a), coronal STIR (b), axial T1-weighted (c), axial T2-weighted (d), and axial proton density-weighted (e) images show geographical areas in both femurs with central fat signal, bordered by a serpiginous peripheral line, due to multifocal osteonecrosis (arrows). As a complication of osteonecrosis, a pathologic fracture of the neck of the right femur with bone marrow and perischeletric edema was identified (a, b). Also note the typical “double line sign” of the osteonecrotic area of the left femur head consisting of inner bright line (granulation tissue) and outer dark line (sclerotic bone) on axial T2-weighted image (d)

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