Skip to main content
Fig. 17 | Insights into Imaging

Fig. 17

From: Imaging side effects and complications of chemotherapy and radiation therapy: a pictorial review from head to toe

Fig. 17

65-year-old woman with viral cirrhosis and hepatocarcinoma previously treated with transarterial embolization with post-treatment persistence of viable tumor (LR-TR viable), then submitted to stereotactic body RT with radiation dose of 40 Gy in 5 fractions. a Contrast-enhanced MRI performed before stereotactic body RT shows the hypervascular HCC (arrow) on arterial phase. b Contrast-enhanced MRI performed two months after treatment showed a size increase of the lesion with reduced enhancement in the central area. c Contrast-enhanced MRI performed four months after stereotactic body RT shows an ill-defined peritumoral enhancement consistent with radiation induced liver disease, that prevents from adequate assessment of tumor margins; the lesion itself shows greater central hypointense area with peripheral enhancement. d Contrast-enhanced CT performed 6 months after stereotactic body RT shows a markedly reduced enhancement of the tumor, as well as reduction of peritumoral enhancement. Therefore, the tumor increase in size in the first follow-up at 2 months was not a true progressive disease and was likely related to RT-related changes. Case courtesy of Dr. Daniele Marin, Duke University Medical Center, Durham (NC), USA

Back to article page