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Fig. 12 | Insights into Imaging

Fig. 12

From: Imaging side effects and complications of chemotherapy and radiation therapy: a pictorial review from head to toe

Fig. 12

Axial CT images of different cases of ChT/RT-related lung toxicity. a shows acute pneumonitis after the first administration of an anti-PD-1 target immunotherapic agent (Pembrolizumab) in a patient with right lung cancer. Also Nivolumab (another anti-PD-1 agent) can cause lung adverse disease with interstitial pneumonitis presenting with organizing pneumonia pattern, as shown in (b, c). An example of radiation-primed cryptogenic organizing pneumonia is reported in (d), which shows the so-called “reverse halo sign” or “atoll sign” in the left lower lobe after RT for breast cancer. e Shows acute and diffuse alveolar hemorrhage in a patient with NSCLC treated with Bevacizumab, with bilateral GGOs caused by blood filling alveolar spaces. Acute lung edema with bilateral smooth lobular septal thickening and GGOs in a patient treated with IL-2 is shown in (f)

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