Table 1 Comparison of patients’ clinical characteristics and CT features of GGNs
Parameters | Malignant GGN (n = 149, 148 patients) | Benign GGN (n = 130, 126 patients) | p value |
|---|---|---|---|
Age (year) | 54.95 ± 11.82 | 53.73 ± 10.26 | 0.366 |
Gender | |||
Female | 95 (64.19) | 63 (50) | 0.018 |
Male | 53 (35.81) | 63 (50) | |
Diameter (mm) | 10.84 ± 4.28 | 9.14 ± 3.68 | 0.003 |
RDR (%) | 48.06 ± 29.05 | 40.35 ± 27.61 | 0.024 |
Location | |||
Right upper lobe | 61 (40.94) | 50 (38.46) | 0.165 |
Right middle lobe | 9 (6.04) | 4 (3.08) | |
Right lower lobe | 18 (12.08) | 29 (20.71) | |
Left upper lobe | 46 (30.87) | 33 (25.38) | |
Left lower lobe | 15 (10.07) | 14 (10.77) | |
Homogeneity | |||
Homogeneous | 22 (14.77) | 30 (23.08) | 0.075 |
Heterogeneous | 127 (85.23) | 100 (76.92) | |
Shape | |||
Round/oval | 37 (24.83) | 55 (42.31) | 0.002 |
Irregular | 112 (75.17) | 75 (57.69) | |
Nodule-lung interface | |||
Well-defined | 103 (69.13) | 73 (56.15) | 0.025 |
Ill-defined | 46 (30.87) | 57 (43.85) | |
Margin | |||
Smooth | 27 (26.21) | 26 (35.62) | 0.18 |
Coarse | 76 (73.79) | 47 (64.38) | |
Other signs | |||
Lobulation | 108 (72.48) | 48 (36.92) | < 0.0001 |
Spiculation | 15 (10.07) | 4(3.08) | 0.021 |
Vacuole | 16 (10.74) | 8 (6.15) | 0.173 |
Pleural traction | 13 (8.72) | 2 (1.54) | 0.008 |
Solid components | 40 (26.85) | 31 (23.85) | 0.566 |
Air bronchogram | 3 (2.01) | 1 (0.77) | 0.713 |