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Table 2 Characteristics of the papers dealing with soft-tissue sarcomas included in the systematic review

From: CT and MRI radiomics of bone and soft-tissue sarcomas: a systematic review of reproducibility and validation strategies

First author Year Aim Tumor Design Reference standard Modality Database size (n) Public data Segmentation
Process Style
Corino [52] 2018 Grading Multiple sarcoma histotypes Retrospective Histology MRI 19 No Manual 3D
Crombé [39] 2020 Metastatic relapse
Survival
Liposarcoma Retrospective Histology Follow-up MRI 35 No Manual 3D
Crombé [42] 2020 Metastatic relapse
Survival
Multiple sarcoma histotypes Retrospective Histology Follow-up MRI 50 No Manual 3D
Crombé [30] 2019 Therapy response Multiple sarcoma histotypes Prospective Histology Imaging MRI 25 No Manual 3D
Crombé [47] 2019 Therapy response Multiple sarcoma histotypes Retrospective Histology MRI 65 No Manual 3D
Crombé [63] 2020 Therapy response
Survival
Liposarcoma Retrospective Histology Follow-up MRI 21 No Manual 3D
Crombé [36] 2020 Therapy response
Survival
Desmoid tumor Retrospective Imaging Follow-up MRI 42 No Manual 3D
Crombé [31] 2020 Metastatic relapse
Survival
Multiple sarcoma histotypes Retrospective Histology Follow-up MRI 70 No Manual 3D
Gao [33] 2020 Therapy response Multiple sarcoma histotypes Prospective Histology MRI 30 No Manual 3D
Hayano [21] 2015 Survival Multiple sarcoma histotypes Prospective Follow-up CT 20 No Manual 2D without MS
Hong [64] 2020 Grading Multiple sarcoma histotypes Retrospective Histology MRI 42 No Manual 3D
Juntu [48] 2010 Benign versus malignant Multiple benign/ malignant histotypes Retrospective Histology MRI 135 No Manual 2D with MS
Kim [65] 2017 Benign versus malignant Multiple benign/ malignant histotypes Retrospective Histology MRI 40 No Manual 3D
Leporq [19] 2020 Benign versus malignant Lipoma
Liposarcoma
Retrospective Histology MRI 81 No Manual 2D without MS
Malinauskaite [23] 2020 Benign versus malignant Lipoma
Liposarcoma
Retrospective Histology MRI 38 No Semiautomatic 3D
Martin-Carreras [34] 2019 Benign versus malignant Myxoma Myxofibrosarcoma Retrospective Histology MRI 56 No Manual 3D
Mayerhoefer [57] 2008 Benign versus malignant Multiple benign/ malignant histotypes
Non-tumoral lesions
Retrospective Histology MRI 58 No Manual 2D with MS
Meyer [66] 2019 Proliferation index Multiple sarcoma histotypes Retrospective Histology MRI 29 No Manual 2D without MS
Peeken [25] 2019 Grading
Survival
Multiple sarcoma histotypes Retrospective Histology Follow-up MRI 225 No Manual 3D
Peeken [27] 2019 Grading
Survival
Multiple sarcoma histotypes Retrospective Histology Follow-up CT 221 Yes Manual 3D
Pressney [14] 2020 Benign versus malignant Lipoma
Liposarcoma
Retrospective Histology MRI 60 No Manual 2D without MS
Spraker [51] 2019 Survival Multiple sarcoma histotypes Retrospective Follow-up MRI 226 No Manual 3D
Tagliafico [26] 2019 Local relapse Multiple sarcoma histotypes Prospective Histology Imaging MRI 19 No Manual 2D with MS
Thornhill [49] 2014 Benign versus malignant Lipoma
Liposarcoma
Retrospective Histology MRI 44 No Semiautomatic 3D
Tian [35] 2020 Metastatic relapse n/a Retrospective Histology Imaging MRI 77 No Manual 3D
Tian [67] 2015 Therapy response
Survival
Multiple sarcoma histotypes Prospective Histology Follow-up CT 20 No Manual 2D without MS
Timbergen [20] 2020 Histotype Desmoid tumor
Multiple sarcoma histotypes
Retrospective Histology MRI 203 No Manual 3D
Vallières [55] 2015 Metastatic relapse Multiple sarcoma histotypes Retrospective Histology Imaging MRI 51 Yes Manual 3D
Vallières [68] 2017 Metastatic relapse Multiple sarcoma histotypes Retrospective Histology Imaging MRI 30 Yes Manual 3D
Vos [40] 2019 Benign versus malignant Lipoma
Liposarcoma
Retrospective Histology MRI 116 No Semiautomatic 3D
Wang [41] 2020 Grading Multiple sarcoma histotypes Retrospective Histology MRI 113 No Manual 3D
Wang [43] 2020 Benign versus malignant Multiple benign/ malignant histotypes Retrospective Histology MRI 206 No Manual 3D
Wang [24] 2020 Benign versus malignant Multiple benign/ malignant histotypes Retrospective Histology MRI 91 No Manual 3D
Wu [18] 2020 Benign versus malignant Multiple benign/ malignant histotypes Retrospective Histology CT 49 No Manual 2D without MS
Xiang [17] 2019 Grading Multiple sarcoma histotypes Retrospective Histology MRI 67 No Manual 2D without MS
Xu [37] 2020 Grading Multiple sarcoma histotypes Retrospective Histology MRI 105 No Manual 3D
Zhang [44] 2019 Grading Multiple sarcoma histotypes Retrospective Histology MRI 37 No Manual 3D
  1. MS multiple sampling