Skip to main content
Fig. 8 | Insights into Imaging

Fig. 8

From: Diagnostic methods and therapeutic options of uveal melanoma with emphasis on MR imaging—Part II: treatment indications and complications

Fig. 8

A 72-year-old woman with radiation-induced panuveitis and diffuse choroidal detachment after proton-beam radiotherapy for uveal melanoma of the left eye. The patient underwent secondary enucleation four years after radiotherapic treatment because of radiation-related inflammatory complications. Axial (a) T2-weighted turbo spin-echo STIR and b contrast-enhanced fat-suppressed T1-weighted images. The choroid is diffusely thickened and detached and displays pronounced enhancement after contrast agent administration (white arrows in b). On T2-weighted image, an exudative collection into the suprachoroidal space is detectable along the lateral aspect of the left eye (white arrowhead). Note the diffuse edematous thickening of the periocular tissues that appear hyperintense on T2-weighted image (white asterisk) and demonstrate marked enhancement on contrast-enhanced T1-weighted image (black asterisk). On c axial DW image (b = 1000 s/mm2), the periocular tissues and detached choroid exhibit restricted diffusion with high signal intensity (white dotted arrow). d Medium magnification showing the histological equivalent of radiologically identified panuveitis: the suprachoroidal compartment is entirely replaced by an acute/suppurative inflammatory process, rich in neutrophils (H&E, original magnification 50×). e Histopathology confirms the presence of a radiotherapy-related choroidal detachment (H&E, original magnification 50×)

Back to article page