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Insights into Imaging
Fig. 6 | Insights into Imaging

Fig. 6

From: Diagnostic methods and therapeutic options of uveal melanoma with emphasis on MR imaging—Part II: treatment indications and complications

Fig. 6

A 58-year-old man with residual fibrotic scar after proton-beam radiotherapy for choroidal melanoma of the right eye. The patient underwent secondary enucleation two years after radiotherapy because of neovascular glaucoma. a Axial T2-weighted turbo spin-echo STIR image demonstrates an intraocular small rounded hypointense mass along the posterior aspect of globe (black arrow). On b contrast-enhanced fat-suppressed T1-weighted image, the mass exhibits mild enhancement (white arrow). Note the pronounced enhancement of the choroid below the irradiated lesion due to radiation-related neoangiogenesis (white arrowhead). c Histological examination showing a well-circumscribed sclero-hemorrhagic nodule composed of ectatic vessels, fibrosis with scattered reactive fibroblasts and abundant component of melanophages; no neoplastic cells are visible (H&E, original magnification 200×). d On higher magnification, within the choroid below the abovementioned nodule, ectatic and thick-walled vessels are evident (H&E, original magnification 400×)

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