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Insights into Imaging
Fig. 8 | Insights into Imaging

Fig. 8

From: Diagnostic methods and therapeutic options of uveal melanoma with emphasis on MR imaging—Part I: MR imaging with pathologic correlation and technical considerations

Fig. 8

A 79-year-old woman with a poorly pigmented choroidal melanoma and hemorrhagic retinal detachment of the right eye. Coronal (a) T2-weighted turbo spin-echo STIR and (b) contrast-enhanced fat-suppressed T1-weighted images show a dome-shaped intraocular lesion along the inferior aspect of globe (white arrows), exhibiting intermediate signal intensity on T2-weighted image and enhancement on contrast-enhanced T1-weighted image. Note the small non-enhancing retinal detachment on both sides of the mass (white arrowheads in b). (c) Histological examination: the radiologically described mass on the posterior wall of the eye is well evident on low magnification; melanoma cells appear poorly pigmented (H&E, original magnification ×25). (d) Higher magnification demonstrating ectatic vessels, responsible for the enhancement of the lesion on post-contrast images. Note the lack of pigment and the presence of scattered melanophages intermingled with neoplastic cells (H&E, original magnification ×100)

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