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Table 2 Clinical and imaging features of common pathologies mimicking medulloblastoma

From: Posterior fossa extra-axial variations of medulloblastoma: a pictorial review as a primer for radiologists

Diagnosis Common features
Meningioma Short duration of symptoms, lack of cranial nerve involvement, and bony hyperostosis
A well-demarcated lesion
Follow the gray matter signal intensity
Cholesteatoma A destructive lesion with bony erosion
Restricted diffusion on diffusion-weighted images
Nerve sheath tumor Destruction of the internal auditory canal
Follow the signal intensity of the white matter
Cystic degeneration and hemorrhagic components are common
Epidermoid inclusion cyst Follow the signal intensity of CSF with incomplete FLAIR suppression
Restricted diffusion and no enhancement on post-contrast images
Metastasis History of a primary malignant lesion
Metastatic work-up to look for other masses
Primary bone tumor Bony origin with erosion and a calcification or ossification pattern
Choroid plexus papilloma Well-defined lesion located in the foramen of Luschka
Feathery appearance with restricted diffusion and intense postcontrast enhancement
Hemangioblastoma Young and middle-aged adults
High intrinsic vascularity, as evidenced by high rCBV values on perfusion MRI
If multiple, strong association with VHL syndrome
Atypical teratoid rhabdoid tumor Heterogenous solid-cystic mass occurring off-midline in children < 3 years of age
Pilocytic astrocytoma Cystic lesion with a pathognomonic mural nodule
Hypodense on CT images
  1. CSF cerebrospinal fluid, FLAIR fluid-attenuated inversion recovery, rCBV relative cerebral blood volume, MRI magnetic resonance images, VHL Von Hippel-Lindau, CT computed tomography