Fig. 2
From: A pictorial review of the utility of CEUS in thoracic biopsies
Male patient with persistent cough. a A CT examination showed focal anterior pleural thickening (arrow). b PET-CT examination demonstrated a small focus of avidity within the pleura thickening. c B mode ultrasound defines the area of pleural thickening but not the smaller focus of avidity seen on PET-CT (d) simultaneous CEUS showed the subpleural area to be hypoenhancing (thick arrow) with a 4-mm focus of hyperenhancement (thin arrows) suggestive of the pathological tissue. e, f Simultaneous B mode and CEUS imaging with an 18-gauge biopsy needle (thin arrows) traversed through the enhancing focus (thick arrow). Histology revealed pleural adenocarcinoma