Table 1 Uniform terminology for tumour response categories
SOR category | SOR threshold criteria | RECIST 1.1 equivalent | RECIST 1.1 threshold criteria* |
|---|---|---|---|
Significant decrease of tumour burden | ≥ 30% decrease in tumour burden and/or qualitative evidence of improvement | Partial response (PR) | ≥ 30% decrease in tumour burden (compared with baseline) |
Slight decrease of tumour burden | ≥ 10–30% decrease in tumour burden and/or qualitative evidence of moderate improvement | n.a. | n.a. |
No significant change of tumour burden | Absence of quantitative or qualitative change of tumour burden | Stable disease (SD) | Criteria for PR and PD are not met |
Slight increase of tumour burden | ≥ 10–20% increase in tumour burden and/or qualitative evidence of moderate worsening | n.a. | n.a. |
Significant increase of tumour burden | ≥ 20% increase in tumour burden and/or qualitative evidence of remarkable worsening | Progressive disease (PD) | ≥ 20% increase in tumour burden (compared with nadir) |