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Fig. 5 | Insights into Imaging

Fig. 5

From: Multiparametric MRI: practical approach and pictorial review of a useful tool in the evaluation of brain tumours and tumour-like lesions

Fig. 5

Targeting biopsy for a non-enhancing tumour. Conventional MRI: a, b Post-contrast T1W and T2W sequences demonstrate a large non-enhancing space occupying mass lesion without significant oedema. Multiparametric MRI: c, d Heterogeneous ADC and rCBV values throughout the lesion. e Multi-voxel MRS clearly shows focal area of very high Cho/Cr (3.1) and very small lactate peak. f Targeted biopsy taken from the area of highest choline peak (arrow). Histopathology shows anaplastic astrocytoma with moderately atypical astrocytic cells in a fibrillary background with a few abnormal mitoses (WHO grade III).

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