Table 3 Studies comparing diagnostic performance of WBMRI and PET-CT
Ref | First author | Year | Population | Use of DWI | Sensitivity of WBMRI (vs. PET-CT) | Specificity of WBMRI (vs. PET-CT) | Accuracy of WBMRI (vs. PET-CT) | Comments |
|---|---|---|---|---|---|---|---|---|
[9] | Jacobs | 2018 | 22 patients with stage IV | Yes | 96% (vs. 80%) | N/R | N/R | ADC values were significantly increased in bone lesions while they were decreased in soft tissue metastases. |
[107] | Schmidt | 2007 | 30 patients with different stages | Yes | 94% (vs. 78%) | 76% (vs. 80%) | 91% (vs. 78%) | WBMRI showed superior accuracy in bone marrow screening compared to PET-CT. |
[86] | Antoch | 2003 | 98 patients with different stages | No | 90% (vs. 93%) | 95% (vs. 95%) | 93% (vs. 94%) | PET-CT showed better performance. However, the WBMRI was performed without DWI. |
[89] | Schmidt | 2008 | 33 patients with breast cancer and suspicious of recurrence | Yes | 93% (vs. 91%) | 86% (vs. 90%) | 91% (vs. 91%) | It was also assessed that staging with WBMRI is feasible at 1.5 and 3 T, noting that scan time is reduced at 3 T with identical resolution. |