Fig. 1

Chest radiograph of a 19-year-old HIV-positive patient with low CD4 count. He presented with cough and dyspnea and was initially being evaluated for possible atypical pneumonia. The chest radiograph showed multiple focal opacities predominantly in the lower lung zones. On CT, there were lung parenchymal nodules/masses of variable sizes which were also intensely FDG avid on PET CT. There was extensive lymphoma involvement elsewhere including in the liver, spleen (splenic activity higher than liver background), and multiple nodal sites above and below the diaphragm. Biopsy of the liver lesion was consistent with DLBCL