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Table 2 Approach to lytic skull vault lesions

From: Imaging of skull vault tumors in adults

Young patient

Fibrous dysplasia (ground-glass matrix)

Eosinophilic granuloma (“button sequestrum”)

Elderly and multiple

Metastasis

Plasma-cell myeloma

Bone-expanding

Fibrous dysplasia (ground-glass matrix)

Hemangioma (“spoke wheel”)

Giant cell tumor (hypervascular, flow-voids)

Aneurysmal bone cyst (hemosiderin levels)

Diffusion-restricting

Epidermal inclusion cyst (previous trauma)

Dermoid cyst (fatty content)