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Table 2 Approach to lytic skull vault lesions

From: Imaging of skull vault tumors in adults

Young patientFibrous dysplasia (ground-glass matrix)
Eosinophilic granuloma (“button sequestrum”)
Elderly and multipleMetastasis
Plasma-cell myeloma
Bone-expandingFibrous dysplasia (ground-glass matrix)
Hemangioma (“spoke wheel”)
Giant cell tumor (hypervascular, flow-voids)
Aneurysmal bone cyst (hemosiderin levels)
Diffusion-restrictingEpidermal inclusion cyst (previous trauma)
Dermoid cyst (fatty content)