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Table 2 CEUS LI-RADS categories

From: CEUS LI-RADS: a pictorial review

Diagnostic categories

Clinical significance

Imaging workup options

Return to routine surveillance

Alternative diagnostic imaging (i.e., CT or MRI)

Repeat CEUS

CEUS LR-NC

Not categorizable (due to image degradation or omission)

–

≤ 3 months*

≤ 3 months**

CEUS LR-1

Definitely benign

6 months**

–

–

CEUS LR-2

Probably benign

6 months**

–

≤ 6 months*

CEUS LR-3

Intermediate probability of malignancy

–

≤ 6 months**

≤ 6 months*

CEUS LR-4

Probably HCC

Multidisciplinary discussion may be needed for consensus management. If neither biopsy nor treatment is planned: repeat or alternative diagnostic imaging in ≤ 3 months

CEUS LR-5

Definitely HCC

Diagnosis of HCC. Multidisciplinary discussion for consensus management.

CEUS LR-M

Probably or definitely malignant, not necessarily HCC

Multidisciplinary discussion for consensus management.

May include alternative or repeat imaging, biopsy, or treatment

CEUS LR-TIV

Tumor in vein

Multidisciplinary discussion for consensus management. May include biopsy or biomarker correlation to determine etiology of TIV: HCC, ICC, other.

  1. **Preferred option in most cases
  2. *Reasonable alternative option. Not recommended