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Fig. 27 | Insights into Imaging

Fig. 27

From: Non-neoplastic hepatopancreatobiliary lesions simulating malignancy: can we differentiate?

Fig. 27

A 32-year-old female with no known medical history presented with chronic epigastric pain and weight loss. Abdominal CT showed a questionable and poorly discernible hypoattenuating mass within the pancreatic uncinate process (not shown). a Axial plane T2W MRI clearly demonstrates a hypointense lesion (arrows) in the uncinate process. b Axial plane DWI image shows focal diffusion restriction at the lesion site (arrows). The restricted area is larger than the actual lesion which may be a helpful finding for differentiation from adenocancer. Biopsy with endoscopic US guidance and subsequent immunohistochemical staining revealed IgG4-related pancreatic disease. With this result, the patient was placed on steroid treatment. c Follow-up imaging 3 months later after systemic steroid treatment confirmed complete resolution of the pancreatic pseudomass

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