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Insights into Imaging
Fig. 5 | Insights into Imaging

Fig. 5

From: Cancer genome landscape: a radiologist’s guide to cancer genome medicine with imaging correlates

Fig. 5

PI3K pathway. a Image showing the PI3K-ATK-mTORC pathway and the blockage of the effector mTORC1/2 by the mTOR inhibitors, such as everolimus. b–d Baseline and restaging contrast-enhanced CT images of a 60-year-old man with metastatic neuroendocrine tumor on everolimus show decreased enhancing component of a liver metastasis (arrowheads), representing response to treatment. Patient developed drug induced pneumonitis while on treatment (arrow) (d)

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