Fig. 4
From: Combining molecular and imaging metrics in cancer: radiogenomics
Box and whisker plots show the relationship of the MRI based phenotypes of (a) size (effective diameter) and (b) enhancement texture (maximum correlation coefficient) with the recurrence predictor models of MammaPrint, Oncotype DX, PAM50 ROR-S, and PAM50 ROR-P. A positive correlation between the selected MR imaging phenotypes of size (effective diameter) and negative correlation with enhancement texture (maximum correlation coefficient) and increasing levels of risk of recurrence for MammaPrint, Oncotype DX, PAM50 ROR-S, and PAM50 ROR-P were observed. A low value of this enhancement texture feature indicates a more heterogeneous enhancement pattern. Reprinted with permission from: Radiology. 2016 Nov;281 [2]:382–391. Epub 2016 May 5. MR Imaging Radiomics Signatures for Predicting the Risk of Breast Cancer Recurrence as Given by Research Versions of MammaPrint, Oncotype DX, and PAM50 Gene Assays. Li H, Zhu Y, Burnside ES, Drukker K, Hoadley KA, Fan C, Conzen SD, Whitman GJ, Sutton EJ, Net JM, Ganott M, Huang E, Morris EA, Perou CM, Ji Y, Giger ML