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Fig. 2 | Insights into Imaging

Fig. 2

From: Advanced imaging in adult diffusely infiltrating low-grade gliomas

Fig. 2

Astrocytoma, grade II with the absence of IDH1 mutation (IDH wild-type), loss of ATRX expression, 20% p53, and 3.3% Ki67 is located on the right temporal lobe on axial MR images. The tumor has a high signal on T2 (a), FLAIR (b), and ADC (c) images and faint enhancement on post-contrast T1-weighted image (d). The tumor has low ITSS on SW image (e) and rCBVmax values compared to normal parenchyma on the DSC-perfusion image (f). The tumor has increased Cho/Cr ratio and low NAA/Cr ratio on the MR spectrum obtained by 144 ms echo time (g). The high-resolution MR spectroscopy by 69 ms of echo time (h) reveals a singlet due to the glutamine-glutamate complex (Glu-Gln), which is consistent with the absence of 2-HG peak and IDH1 mutation

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