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Fig. 1 | Insights into Imaging

Fig. 1

From: Advanced imaging in adult diffusely infiltrating low-grade gliomas

Fig. 1

Grade II astrocytoma with IDH1 mutation, 30% p53, and 3% Ki67 is located on the posterior aspect of the right frontal lobe on axial MR images. There is a mismatch sign on T2 (a) and FLAIR (b) images. The tumor has a high signal on ADC (c) images and does not enhance on post-contrast T1-weighted image (d). The tumor has low rCBVmax values compared to normal parenchyma on the DSC-perfusion image (e). Increased Cho/Cr ratio inside the tumor borders is prominent on both the MR spectrum obtained by 144 ms echo time (f) and colored Cho map (g). The high-resolution MR spectroscopy by 69 ms of echo time (h) reveals the 2-HG peak causing a triplet within the glutamine-glutamate complex (Glu-Gln), which is consistent with the existence of IDH1 mutation

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