Table 1 Diagnostic accuracy measures in non-contrast-enhanced MRI techniques and contrast-enhanced techniques in cerebrovascular disease
Clinical question | Diagnostic performance non-CE | Diagnostic performance CE gold standard or DSA gold standard | Author (year) |
|---|---|---|---|
Detect cerebral venous thrombosis | AUC 0.89 (± 0.03 SD) 2D-TOF MR venography | AUC 0.99 CE T1 3D MP-RAGE | Liang et al. (2001) |
Detect cerebral venous thrombosis | 80% sensitivity, 65% specificity | CE MRV reference standard | Bernard (2017) |
Detect cerebral venous thrombosis | Accuracy 92.7% conv non-contrast-enhanced sequences | Accuracy 98.3 CE T1 3D GRE | Sari (2015) |
Detect cerebral venous thrombosis | Sensitivity/specificity100%/71% 3D PC-MR venography | DSA gold standard | Ozturk et al. (2018) |
Detect intracranial arteriovenous shunting in AVM | AUC 0.97 (95% CI 0.90–1.00) CBF ASL/SWI | AUC 0.93 (95% CI 0.87–0.97) conv MRI including CE T1 and CE MRA, DSA reference standard | Hodel et al. (2017) |
Nidus localization in AVM | Sensitivity 100% CBF ASL | DSA gold standard | Blauwblomme et al. (2015) |
Evaluation of AVM obliteration | AUC 0.94 CBF ASL | DSA gold standard | Kodera et al. (2017) |
Detect arteriovenous shunting and venous drainage in children with AVM | Sensitivity 100% CBF ASL | DSA gold standard | Nabavizadeh et al. (2014) |
Identify fistula site and venous drainage in AV fistula | Kappa 1.00 four-dimensional MR angiography ASL | DSA gold standard | Iryo et al. (2014) |
Detect and localize AV fistula | Sensitivity 91% (95% CI 69–98) CBF ASL | DSA gold standard | Amukotuwa et al. (2016) |
Characterize dural AV fistula: define shunt location/feeding artery/draining vein/Cognard classification | Kappa interreader agreement 1.00/0.92/1.00/1.00 flow-tracking cartography | DSA gold standard | Edjlali et al. (2014) |
Detect intracranial aneurysms | AUC 0.91 TOF MRA | AUC 0.91 CT angiography/DSA gold standard | Hiratsuka et al. (2008) |
Moyamoya Suzuji stage | Accuracy > 86 (0.86–1 range) ASL-4D MRA | DSA gold standard | Uchino et al. (2015) |
Predictor of 24-h DWI lesion in non-reperfused ischemic stroke | AUC 0.76 (95% CI 0.63–0.85) CBF ASL | AUC 0.79 (95% CI 73–84) Tmax DSC | Bivard et al. (2014) |
Detect arterial occlusion in stroke | Accuracy TOF MRA 0.89 | Accuracy CE MRA 0.99 | Dhundass et al. (2019) |