Table 1 Summary of patients with and without visible T1-hyperintensity of the DN and changes in DN/P SI ratio
Patients | Patient sub-group | Mean age ± SD | M/F | No. of exams | Exam no. at first appearance | Mean interval between exams (months) | Time to first appearance (months) | Mean DN/P before first exam | Mean DN/P before last exam | Unpaired t test |
|---|---|---|---|---|---|---|---|---|---|---|
Negative | All | 51 ± 10.5 | 26/81 | 6.75 ± 3.43 | n/a | 10.6 ± 6.2 | n/a | 1.025 ± 0.006 | 1.032 ± 0.005 | p = 0.323 |
Gadobutrol | 54 ± 8.5 | 12/32 | 7.34 ± 3.82 | n/a | 10.43 ± 8.3 | n/a | 1.045 ± 0.008 | 1.046 ± 0.008 | p = 0.970 | |
Gadoterate | 47 ± 11.5 | 8/34 | 7.21 ± 2.86 | n/a | 11.3 ± 4.5 | n/a | 1.001 ± 0.004 | 1.005 ± 0.003 | p = 0.4239 | |
Both | 49 ± 6.3 | 6/15 | 4.62 ± 4.6 | n/a | 9.8 ± 6.7 | n/a | 1.027 ± 0.025 | 1.06 ± 0.014 | p = 0.543 | |
Positive | All | 50 ± 11.5 | 8/42 | 10.21 ± 4.6 | 4.36 ± 2.5 | 10.79 ± 6.92 | 43.48 ± 27.34 | 1.003 ± 0.004 | 1.137 ± 0.012 | p < 0.0001 |
Gadobutrol | 51 ± 11.2 | 1/19 | 11.16 ± 5.4 | 4.79 ± 2.5 | 10.9 ± 6.4 | 48.32 ± 28.7 | 0.998 ± 0.002 | 1.153 ± 0.016 | p < 0.0001 | |
Gadoterate | 42 ± 8.4 | 6/15 | 9.07 ± 3.9 | 3.93 ± 2.4 | 11.0 ± 8.0 | 40.0 ± 27.32 | 1.003 ± 0.004 | 1.110 ± 0.014 | p < 0.0001 | |
Both | 60 ± 6.4 | 1/8 | 10.13 ± 4.7 | 4.13 ± 2.8 | 10.2 ± 6.7 | 38.5 ± 25.5 | 1.004 ± 0.011 | 1.163 ± 0.032 | p = 0.0004 |