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Table 2 Prevalence, clinical significance, and differential diagnosis of the most common types of variants and accessory ossicles in the forefoot

From: Anatomical variation in the ankle and foot: from incidental finding to inductor of pathology. Part II: midfooot and forefoot

Ossicle

Prevalence

Clinical significance

Differential diagnosis

Hallucal sesamoids

Multipartite (gen medial)

2.7–33.5% bilateral—22–85%

Potential sesamoiditis (osteoarthritis—osteonecrosis)

Sesamoid fracture (multipartite)

Absence

rare

Lesser metatarsal sesamoids

2nd digit

0.4%

Asymptomatic (Infection from surrounding soft tissues)

3rd digit

0.2%

4th digit

0.1%

5th digit

4.3%

Interphalangeal joint sesamoids

2–13% ossified 73% nodule in cadaver series

Interposition in joint dislocation. Limitation to joint mobility and painful callosity have been reported

Os vesalianum

0.1 to 1%

Very rarely a source of pathology

Painful conditions similar to the os peroneum syndrome have been reported

Avulsion fractures of the apophysis and base of the fifth metatarsal

Os intermetatarseum

1.2–10%

Pain on palpation of the dorsum of the foot (superficial and deep peroneal nerves compression)

Small fractures of the base of the second metatarsal in Lisfranc fracture—dislocations