Fig. 14

Luminal regrowth detected exclusively by endoscopy. Images show a clear endoscopic view of a regrowth following initial complete clinical response with no relevant radiological findings. a High-resolution T2WI restaging axial image 16 weeks after neoadjuvant therapy shows a low signal intensity scar from 5 to 9 o’clock. Watch-and-wait was offered. b Follow-up exam after 12 months showed less extensive, from 7 to 10 o’clock persistent low signal intensity scar with no signs of regrowth. c DWI (B = 700) was unremarkable. d Endoscopy showed obvious regrowth at 12 months and the patient was sent to salvage resection. Total mesorectal excision was performed; ypT2N0 with free margins was the final result