Fig. 10From: Neuroimaging assessment in Down syndrome: a pictorial reviewCoronal T1/3D reconstructions of a 48-year-old Down syndrome patient with dementia. a Grade 2 anterior cingulate gyrus atrophy (MRI visual rating scale). b Grade 2 orbito-frontal cortex volume loss. c Grade 2 anterior temporal cortex atrophy. d Grade 3 fronto-insular loss of volume. e Grade 4 medial temporal atrophy, including the amygdala and hippocampus. f Grade 3 posterior parieto-occipital cortex atrophyBack to article page