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Table 2 Estimated marginal means of ADC values (mm2/s) at each tumour regions and subgrouped based on SVZ and cortex involvement (MRI-based classification)

From: Pre-operative apparent diffusion coefficient values and tumour region volumes as prognostic biomarkers in glioblastoma: correlation and progression-free survival analyses

Tumoural zone

Tumour regions

Mean

Std. error

95% confidence interval

Lower bound

Upper bound

I CEL contacting SVZ and infiltrating cortex

Normal tissue ADC

.000781

.000061

.000661

.000902

Enhancing tumour ADC

.001305

.000061

.001185

.001425

Proximal oedema ADC

.001443

.000062

.001320

.001565

Distal oedema ADC

.001447

.000069

.001311

.001583

Necrosis ADC

.002489

.000063

.002364

.002614

II CEL contacting SVZ but not involving cortex

Normal tissue ADC

.000742

.000224

.000301

.001184

Enhancing tumour ADC

.001150

.000224

.000709

.001591

Proximal oedema ADC

.001325

.000224

.000884

.001766

Distal oedema ADC

.001750

.000316

.001126

.002374

Necrosis ADC

.001700

.000224

.001259

.002141

III CEL not contacting SVZ but involving cortex

Normal tissue ADC

.000753

.000077

.000602

.000905

Enhancing tumour ADC

.001353

.000077

.001202

.001504

Proximal oedema ADC

.001515

.000077

.001364

.001667

Distal oedema ADC

.001479

.000085

.001313

.001646

Necrosis ADC

.002461

.000082

.002300

.002622

IV CEL neither contacting SVZ nor infiltrating cortex

Normal tissue ADC

.000795

.000224

.000354

.001236

Enhancing tumour ADC

.001375

.000224

.000934

.001816

Proximal oedema ADC

.001545

.000224

.001104

.001986

Distal oedema ADC

.001585

.000224

.001144

.002026

Necrosis ADC

.002715

.000224

.002274

.003156