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Table 3 MR imaging of vascular tumors of different malignancy

From: Vascular tumors in infants and adolescents

Vascular tumors

 

Hemangioma (infantile/congenital)

Tufted angioma/kaposiform hemangioendothelioma

Epitheloid hemangioendothelioma

Angiosarcoma

MRI morphology

Solid, frequently homogeneous well-defined mass

Diffuse infiltrating mass permeating all soft tissue structures

Solid mass with ill-defined margins

Diffuse inhomogeneous mass, infiltrating all tissue types

MRI signal

T1 pre-contrast

Isointense to muscle

Isointense to muscle

Isointense to muscle

Isointense to muscle

T2 (to be performed with fat saturation)

Hyperintense to muscle

Hyperintense to muscle, septal architecture perpendicular to the skin, often with edema

Moderate hyperintense to muscle

Hyperintense to muscle

Fat-saturated T1 post-contrast

Hyperintense to muscle and flow-voids

Hyperintense to muscle, septal enhancement

Moderate hyperintense to muscle

Hyperintense to muscle (central necrosis frequent)

MRI flow-characteristics

MR-angiography

Fast-flow, tumor blush

Fast flow, tumor blush

Slow flow

Slow-flow

Imaging differential diagnosis

Venous (in case of slow flow hemangioma) or arteriovenous malformation (in case of fast-flow), KHE, macular stains/capillary malformation, soft tissue sarcoma

Hemangioma, soft tissue sarcoma, extraosseus Ewing sarcoma, kaposiform lymphangiomatosis

Hemangioma (such as epitheloid hemangioma), HCC (in case of liver manifestation), lymphoma (in case of lymphatic manifestation), sarcoma

Can mimic any malignant highly vascularized tumor (breast, soft tissue, bone, visceral, head, and neck), intravascular angiosarcoma can resemble thrombosis or atheroma