Fig. 4From: Multimodality imaging of indolent B cell lymphoma from diagnosis to transformation: what every radiologist should knowA 65-year-old woman with Waldenstrom macroglobulinemia treated with chemotherapy and hematopoietic stem cell transplant and new onset fever, neutropenia, and increased LDH. a Axial CT image acquired during portal venous phase six months before the onset of new symptoms shows a hypodense lesion in the spleen. b Axial CT image acquired during portal venous phase at the time of symptom onset shows increased size and decreased density of the splenic lesion. Biopsy of the lesion confirmed histologic transformation to diffuse large B cell lymphomaBack to article page