Fig. 8
An 8-year-old patient with high-grade tectal plate glioma (white arrow). a Post-contrast T1-weighted (+C) and magnetization transfer (MT) images were obtained before (top row) and after (bottom row) chemoradiotherapy; and (b) the corresponding MT ratio histograms of lesion are as shown. The magnetization transfer acquisition comprised a set of four geometry-matched 3D-GRE scans: two flip angles (4 and 24°), with/without MT pulse (1.5 kHz offset) on a 1.5 T MR system. Note the reduction in the MT ratio (histogram in b) associated with response to treatment, accompanied by slight increase in size and enhancement of the tumor (a). [Images courtesy of Dr. Neil P. Jerome, Norwegian University of Science and Technology]