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Insights into Imaging
Fig. 22 | Insights into Imaging

Fig. 22

From: How clinical imaging can assess cancer biology

Fig. 22

Whole-body DWI evaluation in a 72-year-old man with metastatic prostate cancer treated with (docetaxel + prednisone). A comparison between images pre (left) and posttherapy (right) demonstrated that tumor volume decreased (1280 cm3 → 640 cm3) and mean ADC moved from 0.7 to 1.61 confirmed an increasing % of voxels at higher ADC values after therapy consistent with reductions in cellularity due to tumor necrosis. However, tumor response was heterogeneous in this patient and there were some anatomical areas that presented a limited tumor response (black dotted circle on lumbar spine and black arrows)

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