Fig. 14
From: Brain tumour post-treatment imaging and treatment-related complications
Radiation-induced leukoencephalopathy. A 47-year-old female with a history of multiple intracranial thyroid carcinoma metastases (arrows). The patient received WBRT and then developed gradual cognitive decline over the subsequent few years. Imaging performed 3 years after WBRT demonstrates extensive periventricular T2 FLAIR hyperintensity (arrowheads), more than would be expected for age-related microvascular disease, consistent with radiation-induced leukoencephalopathy. Note the relative sparing of subcortical U fibres