Fig. 11

Radiation-induced vasculopathy and mineralising microangiopathy. A 35-year-old male with a history of radiation for craniopharyngioma (brackets). The patient went on to develop multiple strokes over subsequent years with MRA images demonstrating multiple areas of severe stenosis of the intracranial vasculature, most notable in the basilar artery and left supraclinoid ICA (arrows); this is compatible with radiation-induced vasculopathy. CT demonstrates dense calcifications in the subcortical white matter and basal ganglia (arrowheads), consistent with mineralising microangiopathy