From: Imaging presentation of pancreatic neuroendocrine neoplasms
 | US | CEUS | CT | MR | |
---|---|---|---|---|---|
Typical P-NENs | Well-marginated hypoechoic with sharp margins | Hypervascular with rapid and intense enhancement | Isodense or slightly hypodense, well-defined, hyperdense in arterial phase, hyperdense or isodense in portal phase | Well-defined, hypointense on T1W and hyperintense on T2W (better conspicuity in FAT-SAT) Clear restriction signal at DWI Hypervascular in arterial phase and isointense or slightly hyperintense in portal phase | |
Atypical P-NENs | Hypoenhancing pattern | Â | Hypovascular | Hypodense in arterial phase, possible enhancement in portal and late phases | Isointense or slightly hyperintense on T2-weighted sequences No strong restriction at DWI Hypointense in arterial phase, possible enhancement in portal and late phase |
Calcified pattern | Hyperechoic areas with prominent posterior acoustic shadowing | Â | Hyperdense areas with high HU values | Signal void artefact | |
Intraductal growth | Â | Â | Â | Filling defect at MRCP Possible enhancement after contrast media | |
Intravessel growth | Â | Intravessel vascularized thrombus | Intravessel vascularized thrombus | Absence of flow void artefact Intravessel vascularized thrombus | |
Cystic pattern | Anechoic lesion delimited by wall and possible inner septa | Hypervascular enhancement of wall and septa | Hypodense cystic portion Hypervascular enhancement of wall and septa | Hypointense in T1W, hyperintense in T2W Hypervascular enhancement of wall and septa |