Skip to main content

Table 1 Cardiac MR characteristics of different stages of HCM

From: Phenotypes of hypertrophic cardiomyopathy. An illustrative review of MRI findings

  Cardiac MR imaging
   Late-gadolinium enhancement (LGE)
HCM stage Morphological and functional features Prevalence % / LV mass Location SCD risk/year
Subclinical Normal/borderline myocardial hypertrophy
Myocardial crypts
Mitral valve leaflets elongation
Normal LA diameter
Myocardial trabeculations
Myocardial fibrosis
Normal LV EF
Rare Limited Mid-wall Exceptional
Classic (75%) Myocardial hypertrophy
LVOT obstruction (70%)
Mid or moderate LA dilatation
Diastolic dysfunction
LV EF > 65%
< 50% 2% Mid-wall 0,5–1%
Adverse remodelling (15–20%) Progressive LV wall thinning
Reduction/loss of LVOT
Moderate/severe LA dilatation
Diastolic dysfunction
LV EF: 50–65%
> 50% 10–15% Mid-wall/transmural 3–5%
End-stage (5–10%) Dilated form
Restrictive pattern
LV EF < 50%
75–100% > 25% Mid-wall/transmural 10%
  1. LV left ventricle, EF ejection fraction, SCD sudden cardiac death, LA left atrium, LVOT left ventricular outflow tract