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Fig. 3 | Insights into Imaging

Fig. 3

From: The amount of calcifications in pseudoxanthoma elasticum patients is underestimated in computed tomographic imaging; a post-mortem correlation of histological and computed tomographic findings in two cases

Fig. 3

Vascular calcifications. A and B: Extensive calcifications, on the CT scan seen as more or less circumferential calcifications in a longer segment of the vascular wall, were present around the internal elastic lamina and in the media of the vessels of the lower extremities [here the anterior tibial artery (<)]; calcifications are marked with a black line in A. C and D. The same internal elastic lamina and medial calcifications were visible in the gastroepiploic artery, located along the greater curvature of the stomach, in both the histology (calcifications are marked in C) and CT scan (<). E and F: In most of the other large- and middle-sized arteries, variable amounts of calcified elastic fibres were seen in the media (in elastic arteries) and/or around the internal and external elastic lamina (marked). These small calcifications could not be detected on CT scans, on which also many atherosclerotic intimal calcifications were visible (i = intima, m = media, a = adventitia; dotted lines indicate internal and external elastic lamina)

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