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Table 1 Sample of published studies of radiological error

From: Error and discrepancy in radiology: inevitable or avoidable?

Year

Author

Ref

Material

Key points

Comments

2001

Goddard et al.

[11]

Various

Clinically significant error rate of 2–20%, depending on radiological investigation

 

1981

Forrest et al.

[12]

Retrospective review of previous chest x-rays (CXRs) in patients subsequently diagnosed with lung cancer

False-negative rate of 40%

Lesions visible but not reported on prior studies

1983

Muhm at al

[13]

Lung cancers detected by plain radiography screening

90% of cancers detected visible in retrospect on prior radiographs going back months or, in some cases, years (53 months in one case)

 

1993

Harvey et al.

[14]

Review of prior mammograms in patients in whom impalpable breast cancer subsequently diagnosed by mammography

Evidence of carcinoma identifiable on prior studies in 41% when blindly reinterpreted, and in 75% when reviewers were aware of subsequent findings

 

1999

Quekel et al.

[15]

Non-small cell lung cancer diagnosed on plain CXR

19% missed diagnosis rate

16-mm median diameter of missed lesions, median delay in diagnosis of 472 days

1949

In Robinson (1997)

[3]

CXR in patients with suspected TB

Interpreted differently by different observers in 10–20%

 

1990, 1994

Markus et al., Brady et al.

[16, 17]

Barium enema

Average observer missed 30% of visible lesions

Supposed gold standard of colonoscopy also subject to error

1999

Robinson

[18]

Emergency dept. plain radiographs

Major disagreement between two observers in 5–9% of cases

Estimated error incidence per observer of 3–6%

1997

Tudor et al.

[19]

Plain radiographs

Mean accuracy: 77% without clinical information, 80% with clinical information. Modest improvements in sensitivity, specificity and inter-observer agreement with clinical information

Five experienced radiologists reported mix of validated normal and abnormal studies 5 months apart. No clinical information on first occasion, relevant clinical information provided on second occasion

2008

Siewert et al.

[20]

Oncologic CT

Discordant interpretations in 31–37%, with resultant change in radiological staging in 19%, and change in patient treatment in up to 23%

 

2007

Briggs et al.

[21]

Neuro CT & MR

13% major & 21% minor discrepancy rates (undercalls, overcalls & misinterpretations)

Specialist neuroradiologist second reading of studies initially interpreted by general radiologists