Fig. 3
From: Systemic treatment in breast cancer: a primer for radiologists
82-year-old woman with estrogen and progesterone receptor-positive breast cancer with bony metastases being treated with systemic chemotherapy. a Coronal pretreatment CT image of the lumbar spine and pelvis in bone window settings shows a predominantly lytic lesion involving L3 and L5 vertebrae (arrows) and left iliac bone (arrowhead). b Coronal CT image of the lumbar spine and pelvis after 4 months of therapy shows progressive sclerotic changes involving L3 and L5 vertebrae (arrow) and left iliac (arrowhead) lesions representative of treatment effect. This response is in agreement with patient’s improved clinical status and tumour marker levels