Skip to main content

Table 2 Overview of the diagnostic performance of individual conventional CMR criteria and Lake Louise criteria for myocardial characterization in AM; articles are listed in chronological order (see specific references in the text)

From: Lights and shadows of cardiac magnetic resonance imaging in acute myocarditis

First author (reference) Year N EGEr T2 ratio LGE 2/3 Positive criteria (LLc) Reference standard
Abdel-Aty [16] 2005 48 Se 80 Se 84 Se 44 Se 76 Clinical/coronary angiography
Spec 68 Spec 74 Spec 100 Spec 95
Acc 74 Acc 79 Acc 71 Acc 85
Röttgen [33] 2011 131 Se 49 Se 58 Se 31 / EMB
Spec 74 Spec 57 Spec 88
Acc 57 Acc 58 Acc 50
Stensaeth [32] 2012 42 Se 31 Se 57 Se 64 Se 76 Clinical/coronary angiography
Spec - Spec - Spec - Spec -
Acc - Acc - Acc - Acc -
Lurz [30] 2012 70 Se 76 Se 64 Se 74 Se 81 EMB
Spe 53 Sp 65 Spec 65 Spec 71
Acc 70 Acc 63 Acc 71 Acc 79
Šramko [36] 2013 42 Se 40 Se 7 Se 87 Se 53 EMB
Spec 96 Spec 100 Spec 44 Spec 93
Acc 76 Acc 66 Acc 60 Acc 78
Chu [13] 2013 45 Se 66 Se 69 Se 77 Se 80 Clinical/coronary angiography
Spec 90 Spec 100 Spec 60 Spec 90
Acc 72 Acc 76 Acc 73 Acc 82
Francone [31] 2014 57 Se 61 Se 47 Se 60 Se 61 EMB
Spec - Spec - Spec - Spec -
Acc - Acc - Acc - Acc -
Radunski [34] 2014 125 Se 63 Se 76 Se 61 Se 84 Clinical/coronary angiography
Spec 71 Spec 42 Spec 100 Spec 57
Acc 59 Acc 70 Acc 67 Acc 79
Luetkens [21] 2014 66 Se 83 Se 79 Se 75 Se 92 Clinical/coronary angiography
Spec 42 Spec 61 Spec 100 Spec 80
Acc 60 Acc 68 Acc 91 Acc 85
Pooled data    Se 60 Se 63 Se 59 Se 77  
Spec 68 Spec 64 Spec 85 Spec 81
Acc 63 Acc 63 Acc 71 Acc 78
  1. EGEr early gadolinium enhancement ratio = enhancementmyocardium/enhancementskeletal muscle, T2 ratio = signal intensitymyocardium/signal intensityskeletal muscle, LGE late gadolinium enhancement, LLc Lake Louise criteria, Se sensitivity, Spec specificity, Acc diagnostic accuracy, EMB endomyocardial biopsy