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Table 1 Summary of AHA guidelines regarding the follow-up of patients with Kawasaki disease, starting at 1 year

From: Cardiovascular imaging in children and adults following Kawasaki disease

Risk level Diagnostic testing Interval Invasive testing
No CAA Cardiovascular risk assessment 5 years None
Transient CAAa Cardiovascular risk assessment 3–5 years None
Small-medium CAA (>3 mm but <6 mm, z-score 3–7) Cardiovascular risk assessment
Echocardiogram + ECG
1 year
1 year
Invasive CAG if non-invasive test suggests ischemia
Stress test with MPI 2 years
Large CAA (≥6 mm) or Multiple or complex CAA in 1 artery Echocardiogram + ECG one half year Invasive CAG after 6–12 months and if any test or clinical finding suggests ischemia
Stress test with MPI 1 year
Coronary artery obstruction Echocardiogram + ECG one half year Invasive CAG for therapeutic options and if new onset or worsening myocardial ischemia is suggested
Stress test with MPI 1 year
  1. From: Newburger et al., Circulation. 2004;110(17):2747–718
  2. CAG conventional angiography, MPI myocardial perfusion imaging
  3. aDisappearing within 6–8 weeks after the onset of Kawasaki disease