Gadolinium based contrast agents | Elimination pathway | Number of reports | No. administrations (millions) | Excess chelate in preparation | |
---|---|---|---|---|---|
Unconfounded | Confounded | ||||
Omniscan® (Gadodiamide) | Kidney | 438 | 90 | 47 | 25 mmol/L |
Optimark® (Gadoversetamide) | Kidney | 7 | 11 | 0.8 | 35 mmol/L |
Magnevist® (Gadopentetate dimeglumine) | Kidney | 135 | 276 | 95 | 135 mmol/L |
Multihance® (Gadobenate dimeglumine) | 97 % Kidney 3 % Bile | 0 | 8 | 6 | 1 mmol/L |
Primovist® (Gadoxetic acid disodium salt) | 50 % Bile 50 % Kidney | 0 | 0 | 0.15 | (Not known) |
Vasovist® (Gadofosveset trisodium) | 91 % Kidney 9 % Bile | 0 | 0 | 0.05 | (Not known) |
Prohance® (Gadoteridol) | Kidney | 1* | 2 | 2.6 | 1 mmol/L |
Gadovist® (Gadobutrol) | Kidney | 1 | 13 | 12.3 | 2 mmo/L |
Dotarem® (Gadoteric acid) | Kidney | 1** | 11 | 22.4 | 0 |