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Insights into Imaging
Fig. 16 | Insights into Imaging

Fig. 16

From: False positive and false negative diagnoses of prostate cancer at multi-parametric prostate MRI in active surveillance

Fig. 16

A 63-year-old patient underwent MP-MRI prior to routine repeat biopsies as part of his active surveillance protocol. Axial T2W TSE (a), axial ADC map (b) and semi-quantitative contrast curve derived from DCE (c) demonstrate a focal low T2W SI lesion (black arrow) with restricted diffusion (white arrow) and type III kinetics in the left middle peripheral zone. At repeat targeted biopsy using cognitive registration, no corresponding lesion could be identified. With a priori knowledge of the location of the lesion at MP-MRI, the TRUS operator performed three core needle biopsies through the left middle lateral and two core needle biopsies through the left middle medial PZ sextants. Results after targeted biopsies were Gleason 4 + 3 = 7 tumour with two out of three core biopsies in the left middle lateral PZ sextant

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