Fig. 10

A 64-year-old patient with Gleason score 3 + 3 = 6 in <5 % of one core in the left middle PZ underwent MRI prior to enrolment into active surveillance. Axial T2W TSE image (a) demonstrates a low T2 SI focus in the left PZ (dotted arrow) with low SI on ADC (black arrow in b). Based on these findings a diagnosis of potential higher grade tumour was suggested and a repeat biopsy was performed. Saturation biopsies through the left mid PZ revealed only normal prostatic tissue and areas of chronic prostatitis. In retrospect, trace b1000 mm²/s EPI demonstrates low SI (white arrow in c), which indicates that there is no restricted diffusion in this area. Similarly, there is a benign progressive type I enhancement curve on DCE (d), which further argues against a higher grade tumour. Corresponding histopathology slide (e) demonstrates areas of chronic inflammation