Table 2 Patient characteristics
From: The role of MRI in axillary lymph node imaging in breast cancer patients: a systematic review
Author | LN imaging analysis | Time to surgery (days) | n | Prevalence N+ | Mean age in years (range) | T-stage at diag-nosis | Histologic type | Pathologic analysis |
|---|---|---|---|---|---|---|---|---|
Yoshimura et al. | N-N | “Preoperative MRI”, n.o.s. | 202 | 40.0 % | 55 (30–86) | T1-T3 | PT, ST, scirrhous, other | Sectioned long-axis |
Kvistad et al. | P-P | “Before surgery”,n.o.s | 65 | 37.0 % | 59.4 (38–79) | T1-T4 | IDC, ILC, MC, tubular, adenocarcinoma | Histopathological examination n.o.s. |
Michel et al. | P-P and N-N | 2 days (range 1–6 days) | 18 | 61.1 % | 53 (22–76) | T1-T4 | NR | LN regarded as positive when tumour cells were present at light microscopy, independent from immunohistochemical staining results. |
Harada et al. | N-N | Mean 1.2 days | 33 | 19.0 % | 58 (36–77) | T1-T4 | PT, ST, scirrhous, medullary, MC, apocrien, SC, spindle cell | Sectioned long-axis, H&E staining, conventional microscopic examination |
Orguc et al. | N-N | NR | 155 | 25.8 % | 43 (28–76) | NR | NR | NR |
Fornasa et al. | One LN/ALND/patient | 14 days | 43 | 44.2 % | 58 (39–78) | NR | IDC, ILC | Position of the LN and long × short axis |
He et al. | N-N | “After MRI”, n.o.s. | 79 | 12.0 % | 44 (20–67) | NR | DCIS, IDC, ILC, lymphoma | Each LN MRI removed, residual fatty tissue examined, LN sliced 4-mm sections, 3-μm-thick slices cut from each section, stained with H&E |
Scaranelo et al. | P-P | “After MRI”, n.o.s. | 61 | 43.0 % | 53 (33–78) | NR | NR | Embedded in paraffin blocks for histopathologic evaluation n.o.s. |
Hwang et al. | P-P | “After MRI”, n.o.s. | 349 | 26.4 % | 51.3 (25–79) | Only T1 | IDC, ILC, MC, others | Intraoperative frozen section, H&E staining. Remaining portions SLNB; sectioning and immunohistological assay |
Luo et al. | N-N | “Preoperative MRI”, n.o.s. | 36 | 57.0 % | 53 (30–63) | T1-T3 | DCIS, IDC, ILC, other | Analysed and examined by pathologist n.o.s. |
Kamitani et al. | P-P and N-N | NR | 108 | 23.6 % | 54.9 (34–84) | Tis-T3 | DCIS, IDC,ILC, MC, metaplastic | NR |
Basara et al. | P-P and N-N | NR | 110 | 24.0 % | Benign 47 (19–73); malignant 43 (29–70) | NR | IDC, ILC, IDC+ILC, IDC+MC, IDC+pleomorphic, medullary, malignant phyllodes | NR |
Hieken et al. | P-P and N-N | ‘Preoperative MRI”, n.o.s. | 505 | 30.1 % with N0i+, 27.3 % without N0i+ | 62 (24–91) | T1-T4 | IDC, ILC, mixed mammary carcinoma, other | Pathology was reviewed and the presence and extent of axillary nodal disease was verified n.o.s. |
Abe et al. | P-P | NR | 50 | 32.0 % | 59.9 (33–83) | T1-T3 | IDC, ILC | Pathologically confirmed with SLNB or ALND n.o.s. |
Li et al. | N-N | NR | 35 | 42.0 % | NR (30–58) | T1-T2 | IDC, ILC, tubular | Parallel slices 2–3 mm thickness and stained with H&E |
An et al. | P-P | ‘Preoperative MRI”, n.o.s. | 215 | 61.4 % | 50 (26–83) | T1-T3 | IDC, ILC, MC, invasive micro papillary carcinoma, metaplastic, medullary | Sections stained with H&E |